🪶Indigenous / Native American

American Feverfew

Parthenium integrifolium

About American Feverfew

American Feverfew (Parthenium integrifolium) is a herb used in the Indigenous / Native American tradition to help with Fever, Immune Support, Kidney Support, and Inflammation. The aerial parts and leaves are the parts traditionally used, taken internally.

Botanical background

Parthenium integrifolium is a species of flowering plant in the aster family known by the common names wild quinine, American feverfew, and eastern feverfew. It is native to the eastern and midwestern United States.

Source: Wikipedia, via iNaturalist

Parts used

Aerial Parts · internalLeaves · internal
🍵

Tea / Infusion

1–3 cups daily
  • Steep 1–2 tsp of dried American Feverfew in freshly boiled water for 5–10 minutes.
  • Cover while steeping.
  • Strain and drink.
💧

Tincture

20–40 drops in water, 2–3× daily
  • Pack dried American Feverfew into a jar and cover with 40–60% alcohol.
  • Seal and steep for 4–6 weeks, shaking daily.
  • Strain and store in a dark dropper bottle.
💊

Powder / Capsule

500 mg – 1 g, 1–3× daily
  • Grind dried American Feverfew into a fine powder.
  • Fill size 00 capsules or stir into smoothies or honey.

Pregnancy, Breastfeeding & Children

No herb-specific pregnancy/child safety research is documented for American Feverfew in our references — the guidance below is based on its general effect category, not research on American Feverfew itself. Always confirm with a midwife, doctor, or pediatrician.

Pregnancy

Use Caution

This herb has a diuretic (fluid-eliminating) effect. Pregnancy already involves significant fluid/electrolyte shifts, so diuretic herbs are generally used cautiously and in moderation rather than as a routine remedy — this is a general, mechanism-based caution, not herb-specific research.

Breastfeeding

Use Caution

Diuretic herbs are traditionally thought to potentially reduce milk supply through fluid loss — generally used cautiously while establishing or maintaining supply.

Children

Use Caution

Children are more sensitive to fluid and electrolyte shifts — diuretic herbs are generally used cautiously and under guidance.

As a member of the Asteraceae (ragweed/daisy) family, this herb carries a real chance of cross-reaction in anyone allergic to ragweed, chrysanthemums, marigolds, or daisies — introduce cautiously if there's a known allergy.

Contraindications

  • Autoimmune conditions (lupus, MS, RA) — may overstimulate immune response
  • Significant kidney impairment — diuretic herbs may worsen renal function

Warnings

⚠️ Kidney Disease

Some diuretic herbs are contraindicated in those with kidney disease. Consult your doctor if you have impaired kidney function.

⚠️ Allergic Reactions

Discontinue immediately if you experience rash, itching, swelling, or difficulty breathing.

⚠️ Not Medical Advice

This information is for educational purposes only. Always consult a qualified healthcare provider before using herbal remedies.

Drug & herb interactions

May affect immune activity

Watch for: Immunosuppressants (for transplant or autoimmune conditions)

Immune-stimulating herbs can work against immunosuppressive therapy.

May have a diuretic effect

Watch for: Diuretic medications and lithium

Additive fluid loss can affect electrolyte balance and change how the body clears lithium.

Where to find in nature

Native region

North America

Climate

Varied — temperate to subarctic

Habitat

Prairies, woodlands, wetlands, and mountain meadows of North America

🌿 To see American Feverfew growing, visit botanical gardens, university plant collections, or specialist herb nurseries near you. If foraging in the wild, always work with an expert identifier — never consume a plant you are not 100% certain of.

Where to buy

In store

  • Health food stores (Whole Foods, Natural Grocers, Holland & Barrett, GNC)
  • Naturopathic clinics and integrative medicine practices
  • Specialist herbal apothecaries and herbalist practices
  • Farmers markets with herb vendors

Online

iHerb

Wide selection of standardised extracts, capsules, and powders with lab testing

Mountain Rose Herbs

Premium bulk dried herbs — certified organic, ethically sourced

Starwest Botanicals

Large selection of certified organic bulk herbs and powders

Herb Pharm

High-quality liquid extracts and tinctures, rigorous quality standards

Amazon

Convenient — verify brand certifications and check third-party testing

Etsy

Small-batch artisan herbalists, hand-harvested and wildcrafted herbs

Quality tips

When buying American Feverfew, look for: certified organic labelling, clearly stated country of origin, third-party lab testing for heavy metals and pesticides, and a batch expiry date. Standardised extracts offer consistent dosing; bulk dried herbs are more economical for regular use. Avoid very cheap, unlabelled products — quality varies enormously.