πŸͺΆIndigenous / Native American

Devil's Club

Oplopanax horridus

About Devil's Club

Devil's Club (Oplopanax horridus) is a herb used in the Indigenous / Native American tradition to help with Diabetes, Immune Support, Arthritis, and Stress. The aerial parts and leaves are the parts traditionally used, taken internally.

Botanical background

Devil's club or devil's walking stick (Oplopanax horridus, Araliaceae; syn. Echinopanax horridus, Fatsia horrida) is a large understory shrub endemic to the arboreal rainforests of the pacific northwest, but also disjunct on islands in Lake Superior. It is noted for its large palmate leaves and erect, woody stems covered in noxious and irritating spines. It is also known as Alaskan ginseng and similar names, although it is not a true ginseng.

Source: Wikipedia, via iNaturalist

Parts used

Aerial Parts Β· internalLeaves Β· internal
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Tea / Infusion

1–3 cups daily
  • Steep 1–2 tsp of dried Devil's Club in freshly boiled water for 5–10 minutes.
  • Cover while steeping.
  • Strain and drink.
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Tincture

20–40 drops in water, 2–3Γ— daily
  • Pack dried Devil's Club into a jar and cover with 40–60% alcohol.
  • Seal and steep for 4–6 weeks, shaking daily.
  • Strain and store in a dark dropper bottle.
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Powder / Capsule

500 mg – 1 g, 1–3Γ— daily
  • Grind dried Devil's Club into a fine powder.
  • Fill size 00 capsules or stir into smoothies or honey.
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Topical / Poultice

1–2Γ— daily as needed
  • Mash fresh Devil's Club or mix the powder with a little water to form a paste.
  • Apply to the affected area for 20–30 minutes.
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Infused Oil

Massage into affected area 1–2Γ— daily
  • Fill a jar with dried Devil's Club.
  • Pour over a carrier oil until submerged.
  • Leave for 4–6 weeks, then strain.
  • Use topically or as a salve base.
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Herbal Bath

2–3Γ— per week as needed
  • Brew 4–6 tbsp of Devil's Club in 1 litre of hot water for 15 minutes, strain, and add to a warm bath.
  • Soak for 20–30 minutes.

Contraindications

  • Pregnancy & breastfeeding β€” insufficient safety data; consult your doctor
  • Children under 12 β€” therapeutic dosage not established
  • Autoimmune conditions (lupus, MS, RA) β€” may overstimulate immune response
  • CNS medications (benzodiazepines, SSRIs, MAOIs) β€” may potentiate sedative or serotonergic effects
  • Diabetes medications β€” may enhance hypoglycaemic effect; monitor blood glucose closely

Warnings

⚠️ Pregnancy & Breastfeeding

Safety during pregnancy and breastfeeding has not been established for most herbal remedies. Consult your midwife or doctor before use.

β›” Diabetes Medications

May enhance the blood sugar–lowering effect of insulin or oral diabetes medications. Monitor blood glucose closely.

⚠️ Sedatives & Antidepressants

May potentiate the effects of sedative, anxiolytic, or antidepressant medications. Use with caution alongside any CNS-active drugs.

⚠️ Allergic Reactions

Discontinue immediately if you experience rash, itching, swelling, or difficulty breathing.

⚠️ Not Medical Advice

This information is for educational purposes only. Always consult a qualified healthcare provider before using herbal remedies.

Drug & herb interactions

May affect blood sugar

Watch for: Insulin and oral diabetes medications (metformin, sulfonylureas)

Additive blood-sugar-lowering effects can risk hypoglycemia β€” monitor glucose closely.

May affect immune activity

Watch for: Immunosuppressants (for transplant or autoimmune conditions)

Immune-stimulating herbs can work against immunosuppressive therapy.

May have a calming/sedative effect

Watch for: Benzodiazepines, sleep medications, other sedative herbs, and alcohol

Combined CNS-depressant effects can cause excessive drowsiness or impaired coordination.

Where to find in nature

Native region

North America

Climate

Varied β€” temperate to subarctic

Habitat

Prairies, woodlands, wetlands, and mountain meadows of North America

🌿 To see Devil's Club growing, visit botanical gardens, university plant collections, or specialist herb nurseries near you. If foraging in the wild, always work with an expert identifier β€” never consume a plant you are not 100% certain of.

Where to buy

In store

  • Health food stores (Whole Foods, Natural Grocers, Holland & Barrett, GNC)
  • Naturopathic clinics and integrative medicine practices
  • Specialist herbal apothecaries and herbalist practices
  • Farmers markets with herb vendors

Online

iHerb

Wide selection of standardised extracts, capsules, and powders with lab testing

Mountain Rose Herbs

Premium bulk dried herbs β€” certified organic, ethically sourced

Starwest Botanicals

Large selection of certified organic bulk herbs and powders

Herb Pharm

High-quality liquid extracts and tinctures, rigorous quality standards

Amazon

Convenient β€” verify brand certifications and check third-party testing

Etsy

Small-batch artisan herbalists, hand-harvested and wildcrafted herbs

Quality tips

When buying Devil's Club, look for: certified organic labelling, clearly stated country of origin, third-party lab testing for heavy metals and pesticides, and a batch expiry date. Standardised extracts offer consistent dosing; bulk dried herbs are more economical for regular use. Avoid very cheap, unlabelled products β€” quality varies enormously.