🦎Malagasy Traditional Medicine

Madagascar Periwinkle

Catharanthus roseus

About Madagascar Periwinkle

Madagascar Periwinkle (Catharanthus roseus) is a herb used in the Malagasy Traditional Medicine tradition to help with Cancer Support, Diabetes, High Blood Pressure, and Immune Support, among 1 other condition it addresses. The aerial parts and leaves are the parts traditionally used, used both internally and topically.

Botanical background

Catharanthus roseus, commonly known as the Madagascar periwinkle, rose periwinkle, or rosy periwinkle, is a species of flowering plant in the dogbane family Apocynaceae. It is native and endemic to Madagascar, but grown elsewhere as an ornamental and medicinal plant, a source of the drugs vincristine and vinblastine, used to treat cancer. Other English names include Vinca, Cape periwinkle, rose periwinkle, rosy periwinkle, and "old-maid". It was formerly included in the genus Vinca as Vinca rosea.

Source: Wikipedia, via iNaturalist

Parts used

Aerial Parts · bothLeaves · both
🍵

Tea / Infusion

1–3 cups daily
  • Steep 1–2 tsp of dried Madagascar Periwinkle in freshly boiled water for 5–10 minutes.
  • Cover while steeping.
  • Strain and drink.
💧

Tincture

20–40 drops in water, 2–3× daily
  • Pack dried Madagascar Periwinkle into a jar and cover with 40–60% alcohol.
  • Seal and steep for 4–6 weeks, shaking daily.
  • Strain and store in a dark dropper bottle.
💊

Powder / Capsule

500 mg – 1 g, 1–3× daily
  • Grind dried Madagascar Periwinkle into a fine powder.
  • Fill size 00 capsules or stir into smoothies or honey.
🖐️

Topical / Poultice

1–2× daily as needed
  • Mash fresh Madagascar Periwinkle or mix the powder with a little water to form a paste.
  • Apply to the affected area for 20–30 minutes.
🫙

Infused Oil

Massage into affected area 1–2× daily
  • Fill a jar with dried Madagascar Periwinkle.
  • Pour over a carrier oil until submerged.
  • Leave for 4–6 weeks, then strain.
  • Use topically or as a salve base.
🛁

Herbal Bath

2–3× per week as needed
  • Brew 4–6 tbsp of Madagascar Periwinkle in 1 litre of hot water for 15 minutes, strain, and add to a warm bath.
  • Soak for 20–30 minutes.

Pregnancy, Breastfeeding & Children

No herb-specific pregnancy/child safety research is documented for Madagascar Periwinkle in our references — the guidance below is based on its general effect category, not research on Madagascar Periwinkle itself. Always confirm with a midwife, doctor, or pediatrician.

Pregnancy

Use Caution

This herb may affect blood pressure. Since blood pressure changes are a significant pregnancy risk factor (e.g. preeclampsia), herbs in this category are generally used only under medical supervision rather than self-directed — this is a general, mechanism-based caution, not herb-specific research.

Breastfeeding

Use Caution

Generally used cautiously during breastfeeding, particularly if the nursing parent is also on blood pressure medication.

Children

Use Caution

Blood-pressure-active herbs are generally used cautiously in children and typically only under pediatric guidance.

Contraindications

  • Autoimmune conditions (lupus, MS, RA) — may overstimulate immune response
  • Pre-surgery — discontinue at least 2 weeks prior (potential antiplatelet effect)
  • Diabetes medications — may enhance hypoglycaemic effect; monitor blood glucose closely

Warnings

⛔ Diabetes Medications

May enhance the blood sugar–lowering effect of insulin or oral diabetes medications. Monitor blood glucose closely.

⛔ Heart & Blood Pressure Medications

May interact with antihypertensive drugs, blood thinners, or cardiac medications. Do not combine without medical guidance.

⚠️ Allergic Reactions

Discontinue immediately if you experience rash, itching, swelling, or difficulty breathing.

⚠️ Not Medical Advice

This information is for educational purposes only. Always consult a qualified healthcare provider before using herbal remedies.

Drug & herb interactions

May affect blood sugar

Watch for: Insulin and oral diabetes medications (metformin, sulfonylureas)

Additive blood-sugar-lowering effects can risk hypoglycemia — monitor glucose closely.

May affect blood pressure

Watch for: Antihypertensive medications (ACE inhibitors, beta-blockers, calcium channel blockers, diuretics)

Combined use can push blood pressure too high or too low — monitor readings if you take blood pressure medication.

May affect immune activity

Watch for: Immunosuppressants (for transplant or autoimmune conditions)

Immune-stimulating herbs can work against immunosuppressive therapy.

Where to find in nature

Native region

Various global regions

Climate

Varied

Habitat

Cultivated in traditional medicinal gardens, botanical gardens, and herb farms worldwide

🌿 To see Madagascar Periwinkle growing, visit botanical gardens, university plant collections, or specialist herb nurseries near you. If foraging in the wild, always work with an expert identifier — never consume a plant you are not 100% certain of.

Where to buy

In store

  • Health food stores (Whole Foods, Natural Grocers, Holland & Barrett, GNC)
  • Naturopathic clinics and integrative medicine practices
  • Specialist herbal apothecaries and herbalist practices
  • Farmers markets with herb vendors

Online

iHerb

Wide selection of standardised extracts, capsules, and powders with lab testing

Mountain Rose Herbs

Premium bulk dried herbs — certified organic, ethically sourced

Starwest Botanicals

Large selection of certified organic bulk herbs and powders

Herb Pharm

High-quality liquid extracts and tinctures, rigorous quality standards

Amazon

Convenient — verify brand certifications and check third-party testing

Etsy

Small-batch artisan herbalists, hand-harvested and wildcrafted herbs

Quality tips

When buying Madagascar Periwinkle, look for: certified organic labelling, clearly stated country of origin, third-party lab testing for heavy metals and pesticides, and a batch expiry date. Standardised extracts offer consistent dosing; bulk dried herbs are more economical for regular use. Avoid very cheap, unlabelled products — quality varies enormously.