๐Ÿ›๏ธAncient Babylonian Medicine

Mandrake (Lappanu)

Mandragora officinarum

About Mandrake (Lappanu)

Mandrake (Lappanu) (Mandragora officinarum) is a herb used in the Ancient Babylonian Medicine tradition to help with Pain, Fertility, Insomnia, and Ceremonial Use, among 1 other condition it addresses. The aerial parts and leaves are the parts traditionally used, used both internally and topically.

Botanical background

Mandragora officinarum is the type species of the plant genus Mandragora. It is often known as mandrake, although this name is also used for other plants. As of 2015, sources differ significantly in the species they use for Mandragora plants native to the Mediterranean region. In the narrowest circumscription, M. officinarum is limited to small areas of northern Italy and the coast of former Yugoslavia, and the main species found around the Mediterranean is called Mandragora autumnalis,...

Source: Wikipedia, via iNaturalist

Parts used

Aerial Parts ยท bothLeaves ยท both
๐Ÿต

Tea / Infusion

1โ€“3 cups daily
  • Steep 1โ€“2 tsp of dried Mandrake (Lappanu) in freshly boiled water for 5โ€“10 minutes.
  • Cover while steeping.
  • Strain and drink.
๐Ÿ’ง

Tincture

20โ€“40 drops in water, 2โ€“3ร— daily
  • Pack dried Mandrake (Lappanu) into a jar and cover with 40โ€“60% alcohol.
  • Seal and steep for 4โ€“6 weeks, shaking daily.
  • Strain and store in a dark dropper bottle.
๐Ÿ’Š

Powder / Capsule

500 mg โ€“ 1 g, 1โ€“3ร— daily
  • Grind dried Mandrake (Lappanu) into a fine powder.
  • Fill size 00 capsules or stir into smoothies or honey.
๐Ÿ–๏ธ

Topical / Poultice

1โ€“2ร— daily as needed
  • Mash fresh Mandrake (Lappanu) or mix the powder with a little water to form a paste.
  • Apply to the affected area for 20โ€“30 minutes.
๐Ÿซ™

Infused Oil

Massage into affected area 1โ€“2ร— daily
  • Fill a jar with dried Mandrake (Lappanu).
  • Pour over a carrier oil until submerged.
  • Leave for 4โ€“6 weeks, then strain.
  • Use topically or as a salve base.
๐Ÿ›

Herbal Bath

2โ€“3ร— per week as needed
  • Brew 4โ€“6 tbsp of Mandrake (Lappanu) in 1 litre of hot water for 15 minutes, strain, and add to a warm bath.
  • Soak for 20โ€“30 minutes.

Contraindications

  • Pregnancy & breastfeeding โ€” insufficient safety data; consult your doctor
  • Children under 12 โ€” therapeutic dosage not established
  • CNS medications (benzodiazepines, SSRIs, MAOIs) โ€” may potentiate sedative or serotonergic effects

Warnings

โ›” Pregnancy & Breastfeeding

Avoid use during pregnancy or breastfeeding unless under direct supervision of a qualified healthcare provider.

โš ๏ธ Sedatives & Antidepressants

May potentiate the effects of sedative, anxiolytic, or antidepressant medications. Use with caution alongside any CNS-active drugs.

โš ๏ธ Allergic Reactions

Discontinue immediately if you experience rash, itching, swelling, or difficulty breathing.

โš ๏ธ Not Medical Advice

This information is for educational purposes only. Always consult a qualified healthcare provider before using herbal remedies.

Drug & herb interactions

May affect hormone levels

Watch for: Hormone therapies, oral contraceptives, and tamoxifen or similar medications

Some herbs have mild phytoestrogenic or hormone-modulating activity that can interact with hormonal medications.

May have a calming/sedative effect

Watch for: Benzodiazepines, sleep medications, other sedative herbs, and alcohol

Combined CNS-depressant effects can cause excessive drowsiness or impaired coordination.

Where to find in nature

Native region

Various global regions

Climate

Varied

Habitat

Cultivated in traditional medicinal gardens, botanical gardens, and herb farms worldwide

๐ŸŒฟ To see Mandrake (Lappanu) growing, visit botanical gardens, university plant collections, or specialist herb nurseries near you. If foraging in the wild, always work with an expert identifier โ€” never consume a plant you are not 100% certain of.

Where to buy

In store

  • Health food stores (Whole Foods, Natural Grocers, Holland & Barrett, GNC)
  • Naturopathic clinics and integrative medicine practices
  • Specialist herbal apothecaries and herbalist practices
  • Farmers markets with herb vendors

Online

iHerb

Wide selection of standardised extracts, capsules, and powders with lab testing

Mountain Rose Herbs

Premium bulk dried herbs โ€” certified organic, ethically sourced

Starwest Botanicals

Large selection of certified organic bulk herbs and powders

Herb Pharm

High-quality liquid extracts and tinctures, rigorous quality standards

Amazon

Convenient โ€” verify brand certifications and check third-party testing

Etsy

Small-batch artisan herbalists, hand-harvested and wildcrafted herbs

Quality tips

When buying Mandrake (Lappanu), look for: certified organic labelling, clearly stated country of origin, third-party lab testing for heavy metals and pesticides, and a batch expiry date. Standardised extracts offer consistent dosing; bulk dried herbs are more economical for regular use. Avoid very cheap, unlabelled products โ€” quality varies enormously.