Bitter Melon (African variety) Extract

May affect blood sugar

Watch for: Insulin and oral diabetes medications (metformin, sulfonylureas)

Additive blood-sugar-lowering effects can risk hypoglycemia — monitor glucose closely.

May affect immune activity

Watch for: Immunosuppressants (for transplant or autoimmune conditions)

Immune-stimulating herbs can work against immunosuppressive therapy.

Processed by the liver

Watch for: Any medication that is also processed by liver enzymes (ask your pharmacist — this includes many common prescriptions)

Can alter how quickly the body clears certain medications, raising or lowering their effective dose.