🪶Indigenous / Native American

Goldenseal Root Extract

capsule

Conditions addressed

Immune Support Digestive Issues Inflammation Liver Support

Suggested dosage

1–2 capsules daily with food, unless otherwise directed

Pregnancy, Breastfeeding & Children

Pregnancy

Avoid

Goldenseal contains berberine, which is contraindicated in pregnancy — it can cross the placenta and has been linked to newborn jaundice (kernicterus) risk.

Breastfeeding

Avoid

Berberine content means it's generally avoided during breastfeeding due to potential infant jaundice risk.

Children

Avoid

Berberine-containing herbs are contraindicated in newborns/infants due to jaundice risk; used cautiously if at all in older children and never long-term.

Interactions & contraindications

Many prescription medications

Strongly inhibits CYP3A4 and CYP2D6 liver enzymes, which can raise blood levels of many drugs — check with a pharmacist before combining with any prescription medication.

Blood pressure medications

May raise blood pressure.