Harmel (Syrian Rue) Extract
capsule
Conditions addressed
Suggested dosage
1–2 capsules daily with food, unless otherwise directed
Pregnancy, Breastfeeding & Children
Pregnancy
AvoidRue is contraindicated in pregnancy — it has a well-documented history as an abortifacient and can cause serious toxicity (liver/kidney damage, birth defects) even at moderate doses.
Breastfeeding
AvoidContraindicated during breastfeeding due to significant toxicity risk.
Children
AvoidContraindicated in children due to significant toxicity risk.
Interactions & contraindications
Processed by the liver
Watch for: Any medication that is also processed by liver enzymes (ask your pharmacist — this includes many common prescriptions)
Can alter how quickly the body clears certain medications, raising or lowering their effective dose.
May have a diuretic effect
Watch for: Diuretic medications and lithium
Additive fluid loss can affect electrolyte balance and change how the body clears lithium.

