St. John's Wort Nerve Oil
oil-blend
Ingredients
Conditions addressed
How to use
Apply a small amount to the affected area 1–2× daily. Patch-test on a small area of skin first.
- A traditional oil-blend made from St.
- John's Wort flowers, Olive oil, Lavender essential oil, Calendula.
- Prepare in small batches and store in a cool, dark place.
Interactions & contraindications
St. John's Wort flowers
Full profile- CNS medications (benzodiazepines, SSRIs, MAOIs) — may potentiate sedative or serotonergic effects
Pregnancy
AvoidSt. John's Wort has hormone-modulating activity and significantly interacts with many medications (it induces liver enzymes that metabolize a huge range of drugs) — generally avoided in pregnancy, and any use requires medical coordination given the interaction risk alone.
Breastfeeding
AvoidSome case reports describe infant drowsiness/colic when the nursing parent used St. John's Wort; combined with its extensive drug-interaction profile, it's generally avoided while nursing.
Children
AvoidNot typically used in children given its significant drug-interaction profile and hormone-modulating activity.
Antidepressants (SSRIs, SNRIs, MAOIs)
Combined use raises the risk of serotonin syndrome.
Hormonal birth control
Induces liver enzymes that break down oestrogen, reducing contraceptive effectiveness.
Warfarin and other blood thinners
Speeds up drug metabolism, reducing effectiveness and clotting protection.
Immunosuppressants (cyclosporine, tacrolimus)
Can lower drug levels below the therapeutic range — a serious risk for transplant patients.
Triptans and other migraine medications
May increase serotonergic side effects.
Olive oil
- CNS medications (benzodiazepines, SSRIs, MAOIs) — may potentiate sedative or serotonergic effects
No herb-specific pregnancy/child safety research is documented for Olive oil in our references — the guidance below is based on its general effect category, not research on Olive oil itself. Always confirm with a midwife, doctor, or pediatrician.
Pregnancy
Use CautionThis herb is associated with calming/sedative activity. CNS-active herbs are generally used cautiously and short-term in pregnancy rather than as a routine remedy — this is a general, mechanism-based caution, not herb-specific research.
Breastfeeding
Use CautionSedative herbs can cause infant drowsiness via breast milk — generally used cautiously and briefly, watching the baby for excess sleepiness or poor feeding.
Children
Use CautionSedative herbs are dose-sensitive in children, whose smaller body size makes effects less predictable — start low and use short-term under guidance.
May have a calming/sedative effect
Watch for: Benzodiazepines, sleep medications, other sedative herbs, and alcohol
Combined CNS-depressant effects can cause excessive drowsiness or impaired coordination.
Lavender essential oil
Full profile- CNS medications (benzodiazepines, SSRIs, MAOIs) — may potentiate sedative or serotonergic effects
Pregnancy
Likely SafeAromatherapy and mild tea use are widely considered safe throughout pregnancy; internal use of concentrated lavender oil/capsules is less studied and generally kept to topical/inhaled use instead.
Breastfeeding
Likely SafeAromatherapy and topical use are considered compatible with breastfeeding; avoid direct application near the nipple/areola before nursing.
Children
Use CautionDiluted aromatherapy is commonly used to help children sleep. Repeated topical exposure in prepubertal boys has been raised as a possible (though not conclusively proven) factor in rare cases of hormone-related breast tissue changes — avoid regular, undiluted topical use.
Sedatives
Additive drowsiness, particularly with oral use.
Calendula
Full profilePregnancy
Likely SafeTopical use (creams, salves, washes) is widely considered one of the safest herbs in pregnancy for skin healing. Internal/oral use has more limited data and a theoretical emmenagogue reputation, so it's used more cautiously.
Breastfeeding
Likely SafeTopical use is widely used for nipple/skin care while breastfeeding and considered very safe.
Children
Likely SafeWidely used topically for children's skin irritation, diaper rash, and minor wounds — one of the gentlest, most commonly used pediatric topical herbs.
As a member of the Asteraceae (ragweed/daisy) family, this herb carries a real chance of cross-reaction in anyone allergic to ragweed, chrysanthemums, marigolds, or daisies — introduce cautiously if there's a known allergy.
May have a calming/sedative effect
Watch for: Benzodiazepines, sleep medications, other sedative herbs, and alcohol
Combined CNS-depressant effects can cause excessive drowsiness or impaired coordination.

